|Most Common Name:
Known As (other names):|| |
Thebaine: also called paramorphine C19H21NO3
Thebaine is a isoquinoline alkaloid that has no direct
therapeutic use although it is used to synthesize other opiate based compounds
Isoquinoline Alkaloids: A large class of medically active
alkaloids with very varied properties although this group does contain many
constituents from which the most habit forming drugs are made. Precursors of
isoquinoline alkaloids are tyrosine and phenylalanine.
Properties of these alkaloids range widely from
Anti-inflammatory, antifungal, antitumor, antimicrobial and antiviral to
analgesic, narcotic and antitussive, plus virtually everything in-between.
Because of this very wide scope each of the alkaloids should be regarded as
individual and no general properties can be attributed to the group known as
Alkaloids Typical alkaloids are alkaline organic vegetable
substances containing one or more nitrogen atoms. This nitrogen base is capable
of combining with acids to form crystalline salts. Most alkaloids are derived
from amino acids while a few are derived from isoprene units. Alkaloids are white or colourless solids containing oxygen (oxygen
free alkaloids are few and far between and then can only exist as liquids) Most
alkaloids are not water soluble, extraction is normally by tincture.
Alkaloids are found in about one quarter of all flowering plants. Thousands of
alkaloids have been identified from a large number of plants where the alkaloid
can be present in virtually every part of the plant or just a specific part like
rhizome, leaf or seed.
generally have profound physiological impact on the human body and nervous
system effects are predominant.
Many alkaloids are used as extracted and refined compounds derived from the
actual plants or synthesised compounds in pharmaceutical drugs.
Several Alkaloids are banned in many countries because of the extreme impact
on the nervous system (strychnine for instance is a deadly poison in very small
doses) and the habit forming nature of some of the alkaloid compounds.
Thebaine constituent is present in:
Thebaine is present in small quantities which may
not be enough to be a significant dosage for medicinal purposes
or is not the major constituent of this plant/herb
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